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Depressive illness In hypogonadal men whose often lethargic or depressive mood significantly improved under testosterone therapy (59), studies exploring the relationship between gonadal function and depressive episodes showed that testosterone secretion as well as mean levels were decreased significantly in patients (60, 61). The relationship of major depression to stress becomes evident by the increased baseline activity of the HPA axis in patients with the disease. Urinary cortisol secretion is significantly increased in depressive patients, legal dianabol usa is in. This phenomenon is also observed in posttraumatic stress disorder, which can lead to depressive states (62, 63). Decreased testosterone levels in depressive illness can be seen as a permanently downregulated secretion, partially maintaining a state of mood that initiated it in the first place. The effects of depressive illness on androgen levels and vice versa are probably closely related to general stress reactions, in is usa legal dianabol. The mutual character of the feedback mechanism found for testosterone and behaviour may also become evident in this aspect.
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